Team

Members of the consortium include microbiome research groups from across the world.

Martin Blaser (PI), Xuesong Zhang


NYU School of Medicine
Effect of early life antibiotic exposure on type 1 diabetes in NOD mice
Blaser Lab

Alexander Chervonsky (PI)


The University of Chicago
Microbiota, diet and type 1 diabetes
Chervonsky Lab

Jennifer Couper (PI), Tony Papenfuss


University of Adelaide
Environmental Determinants of Islet Autoimmunity (ENDIA) study; Early environmental determinants of pancreatic islet autoimmunity (ENDIA)

Jayne Danska (PI), Alexandra Paun, Christopher Yau


The Hospital for Sick Children
Humoral Immune Response against the Gut Microbiome Distinguishes Healthy Individuals from Subjects at Risk for Type 1 Diabetes
Danska Lab

Julien Diana (PI)


INSERM
Exploring the regulatory roles of antimicrobial peptides on beta-cell function and the immune system: implication for future therapy against type 1 diabetes

Maria Dominguez-Bello (PI), Jincheng Wang

NYU School of Medicine
C-section-like microbiota and alterations of immune responses.
Dominguez-Bello Lab

Marika Falcone (PI)


Fondazione Centro San Raffaele
Exploiting the therapeutic potential of Treg cell-inducing Clostridia in T1D; Nutritional interventions aimed at preventing T1D by inducing a tolerogenic gut environment
Falcone Lab

Emma Hamilton-Williams (PI)


The University of Queensland
A genetic link between gut microbial flora and T1D susceptibility

Len Harrison (PI), Alexandra Roth-Schulze

Walter and Eliza Hall Institute
Maternal-infant microbiomes that precede the onset of islet autoimmunity
Harrison Lab

Curtis Huttenhower (PI), Cesar Arze, Kevin Bonham, Lauren McIver


Harvard T.H. Chan School of Public Health
A bioinformatics platform for the JDRF
Huttenhower Lab

Bana Jabri (PI)


The University of Chicago
Role of Intestinal inflammation in the Pathogenesis of Type-1 Diabetes

Mikael Knip (PI)


University of Turku
Blood Microbiota: A Novel Biomarker of the Leaky Gut Hypothesis in Infants with HLA-Conferred Susceptibility to Type 1 Diabetes and in Children with Clinical Type 1 Diabetes
PEDIA Group

Olle Korsgren (PI)

Uppsala University Hospital
Characterization of duodenal microbiota in children with recent onset Type 1 Diabetes

Alex Kostic (PI), Jonathan Dreyfuss

Joslin Diabetes Center
Examining the role of the microbiome in residual insulin production with the Joslin 50-Year Medalist cohort
Kostic Lab

Riitta Lahesmaa (PI), Harri Lahdesmaki


University of Turku
Systems approach to elucidate microbiota-host response in T1D pathogenesis
Molecular Systems Immunology Group

Graciela Lorca (PI)


University of Florida
Safety, tolerability and host response to Lactobacillus johnsonii

Kathy McCoy (PI)

University of Calgary
Protection from T1D through microbial exposure during pregnancy and early life

Eliana Marino (PI), Josef Wagner

Monash University
Dietary Manipulation of Gut Microbial Metabolites Mitigate Type 1 Diabetes

Jane Mullaney (PI)


The University of Queensland
A link between the gut microbiome and type 1 diabetes

Noah Palm (PI)

Yale University
Gut microbiota dysbiosis drives immunological dysfunction in T1D

James Pearson (PI), Jian Peng

Yale University
Investigating the interaction of the innate immune system and the microbiota in modifying diabetes susceptibility

Eric Triplett (PI), Lexi Ardissone


University of Florida
Separating the Signal from the Noise in the Autoimmune Microbiome for Type 1 Diabetes

Li Wen (PI)


Yale University
Study of oral microbiota in prediction of T1D development

Daniel Whitehead (PI)


Clemson University
Inhibition of Gut Microbial Polysaccharide Metabolism as a Novel Potential Therapeutic for the Prevention of Autoimmunity Associated with Type-1 Diabetes

Ramnik Xavier (PI), Tommi Vatanen


Broad Institute
Early Events in Type 1 Diabetes; Towards a systems level understanding of the gut microbiome and T 1 DM risk
Xavier Lab

Anette-Gabriele Ziegler (PI)


Institute of Diabetes Research, Helmholtz Center Munich
Collaborative Research on Munich cohort studies – Biobank and Database

Danny Zipris (PI), Miranda Kroehl


University of Colorado Denver
Host-Microbiota Interactions in Subjects at Risk for Type 1 Diabetes
Zipris Lab